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When patients are admitted to the hospital due to severe symptoms, we recommend intensive monitoring and supportive care depending on the symptoms that the patient is showing.
The current study indicates that the test compounds produce locomotor depression similar to that of Δ9-THC, and fully substitute for the discriminative stimulus effects of Δ9-THC.
Average horizontal activity counts/10 min as a function of time (10 min bins) and dose.
All of the cathinones fully substituted for the discriminative stimulus effects of Δ9-tetrahydrocannabinol (≥80% drug-appropriate responding).
When clinical presentation and/or initial DOA testing results are inconclusive, additional testing with LC-QTOF-MS can be valuable and is recommended.
He confirmed that he had been vaping an electronic cigarette (e-cigarette) earlier that day just before the onset of his symptoms.
A total of 2 and 3 methamphetamine treated mice fell from the spinning rod 30 min and 2 hr after the administration, respectively.
Much of the in vivo testing of the synthetic cannabinoid compounds have been pre-clinical studies focused on their cannabinoid-like effects or like the present study, focused on their abuse liability.
He confirmed that he had been vaping an electronic cigarette (e-cigarette) earlier that day just before the onset of his symptoms.
Substantial depressant effects were observed within the first 10 min, and maximal depression was observed between 0–30 min following administration.
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