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Combined with non-specific, transient symptoms, clinical recognition of SCRA intoxication is challenging .
In the present study, we investigated the possibilities of neurotoxicity of two synthetic cannabinoids JWH-081 and JWH-210 using behavioral pharmacological approaches.
Since there is currently no robust measure of the reinforcing/rewarding effects of cannabinoids, drug discrimination is currently the best model for assessing abuse liability of cannabinoids.
All five of the compounds in the present study fully substituted with a pretreatment time of 15 min, suggesting a rapid onset of the discriminative stimulus effects.
Since there is currently no robust measure of the reinforcing/rewarding effects of cannabinoids, drug discrimination is currently the best model for assessing abuse liability of cannabinoids.
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