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Each compound was tested in a group of at least six rats using a repeated-measure design such that each rat was tested at all doses of a given drug.
Drug discrimination is a well-known animal model of the subjective effects of drugs and correlates well with abuse liability (Young 2009; Horton et al. 2013).
In 3 cases ADB-BUTINACA was the only substance detected, while in seven other substances of misuse were also detected including other SCRA, opioids, benzodiazepines cocaine and pregabalin.
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In its pure form, it appears as a fine white to off-white crystalline powder and is typically used in laboratory settings for reference standards, pharmacological studies, or forensic analysis.
4F-MDMB-BINACA was hydrolysed via ester hydrolysis forming the 4F-MDMB-BINACA ester hydrolysis metabolite (B22).
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